PT-141
Melanocortin receptor agonist (bremelanotide, PT-141) investigated in melanocortin-signalling research. High-purity, third-party tested, COA included. Research Use Only.
| Purity (HPLC) | ≥ 99.0% |
|---|---|
| Available sizes | 10 mg |
| Physical form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
What is PT-141?
PT-141 (bremelanotide) is a melanocortin-receptor agonist derived directly from Melanotan II — it is the metabolite that results when Melanotan II loses its C-terminal amide group. That single structural difference shifts its receptor profile toward MC4 and away from the MC1-driven pigmentation activity of its parent.
It is supplied as a lyophilized powder at 10 mg. See the reconstitution guide and the reconstitution calculator for preparation.
Research context
Unlike the pigmentation-focused melanocortin analogs, PT-141 is studied for central melanocortin-pathway signalling, principally at the MC4 receptor — a receptor also implicated in appetite and energy-balance research. It is a distinct reference compound within the melanocortin family rather than a variant of the same endpoint.
The standard comparison set is Melanotan II, its structural parent, and the MC1-selective Melanotan I — three molecules differing at a handful of positions and covering the melanocortin receptor family between them. HCG is a useful contrast as a receptor-level endocrine reference of a different class.
Purity and third-party testing
Every batch is independently analysed by Testides and Peptide Test Canada and ships with a certificate of analysis reporting HPLC purity and mass-spectrometry identity. See how to read a certificate of analysis and what a purity figure actually means; our process is on the Research and Quality page.
Handling and storage
Kept cold and protected from light while lyophilized; refrigerated once reconstituted. The storage guide covers both states and bacteriostatic vs. sterile water explains why bacteriostatic water suits a multi-draw vial.
Related research compounds
Browse the melanocortin references and the rest of the full catalogue. New to this area? Start with Peptides 101 or the knowledge hub.
Research Use Only. Supplied strictly for in-vitro laboratory research and development. Not for human or animal consumption, diagnostic, or therapeutic use.
Frequently asked
No. PT-141 is supplied strictly as a reference material for in-vitro laboratory research. It is not for human or animal consumption and is not intended for diagnostic or therapeutic use.
Yes. Every batch is independently tested by Testides and Peptide Test Canada for HPLC purity and mass-spectrometry identity, and ships with a batch-specific certificate of analysis (COA).
PT-141 is available in 10 mg. Per-vial pricing is shown on this page.
PT-141 is supplied as lyophilized powder. Use the reconstitution calculator to work out concentration and dosing volumes for your research, and see the storage and handling guide for temperature and shelf-life guidance. Store the lyophilized vial at -20 degrees C, desiccated and protected from light.
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