
Semax
Heptapeptide (Semax) studied in neurotrophic, BDNF-expression and neuroprotection research models. High-purity, third-party tested reference material with a COA. Research Use Only.
| Sequence / Formula | C37H51N9O10S |
|---|---|
| CAS / Reference No. | 80714-61-0 |
| Purity (HPLC) | ≥ 99.2% |
| Available sizes | 10 mg |
| Physical form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
What is Semax?
Semax is a synthetic heptapeptide built from the ACTH(4-10) fragment of adrenocorticotropic hormone, extended with a Pro-Gly-Pro tail. That tail is the engineering: it protects the peptide from rapid enzymatic breakdown while removing the hormonal activity of the parent molecule, leaving the neuroactive fragment behind.
It is supplied as a lyophilized powder at 10 mg. See the reconstitution guide and the reconstitution calculator for preparation.
Research context
Semax is studied chiefly for its proposed influence on brain-derived neurotrophic factor (BDNF) expression, along with neuroprotection and cognitive-function models. It is one of the more heavily documented compounds in Russian neuropeptide research, where much of the original literature originates.
It is most often examined alongside Selank, which comes from the same research lineage but derives from tuftsin and is studied on anxiolytic rather than neurotrophic endpoints — the two are frequently paired in study designs for exactly that contrast. Cerebroprotein hydrolysate is the other neurotrophic reference in the catalogue.
Purity and third-party testing
Every batch is independently analysed by Testides and Peptide Test Canada and ships with a certificate of analysis reporting high-performance liquid chromatography purity and mass-spectrometry identity. See how to read a certificate of analysis and what a purity figure actually means; our full process is on the Research and Quality page.
Handling and storage
Kept cold and protected from light while lyophilized; refrigerated and used within a shorter window once reconstituted. The storage guide covers both states, and bacteriostatic vs. sterile water explains why bacteriostatic water is the usual diluent for a vial accessed more than once.
Related research compounds
Semax sits in our cognitive and neuro research collection with Selank and DSIP. New to this area? Start with Peptides 101 or browse the full knowledge hub.
Research Use Only. Supplied strictly for in-vitro laboratory research and development. Not for human or animal consumption, diagnostic, or therapeutic use.
Frequently asked
No. Semax is supplied strictly as a reference material for in-vitro laboratory research. It is not for human or animal consumption and is not intended for diagnostic or therapeutic use.
Yes. Every batch is independently tested by Testides and Peptide Test Canada for HPLC purity and mass-spectrometry identity, and ships with a batch-specific certificate of analysis (COA).
Semax is available in 10 mg. Per-vial pricing is shown on this page.
Semax is supplied as lyophilized powder. Use the reconstitution calculator to work out concentration and dosing volumes for your research, and see the storage and handling guide for temperature and shelf-life guidance. Store the lyophilized vial at -20 degrees C, desiccated and protected from light.
What researchers say
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Please review the material itself — purity, packaging, shipping and handling. We cannot publish reviews describing human or animal use, dosing, or health outcomes, because everything we supply is strictly for in-vitro laboratory research. Every review is read before it appears.