Melanotan I
Synthetic alpha-MSH analog (Melanotan I) studied in melanocortin-receptor and pigmentation research. High-purity reference material, third-party tested with a COA. Research Use Only.
| Purity (HPLC) | ≥ 99.0% |
|---|---|
| Available sizes | 10 mg |
| Physical form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
What is Melanotan I?
Melanotan I (afamelanotide) is a synthetic analog of alpha-melanocyte-stimulating hormone, a 13-residue linear peptide modified at two positions to resist enzymatic breakdown. Those substitutions extend its working life substantially compared with native alpha-MSH while leaving its receptor selectivity essentially intact.
It is supplied as a lyophilized powder at 10 mg. See the reconstitution guide and the reconstitution calculator for preparation.
Research context
Research models examine its selective activity at the MC1 receptor and its role in stimulating melanogenesis, making it a reference compound in pigmentation and photoprotection study designs.
That MC1 selectivity is the whole basis of the comparison researchers draw with Melanotan II, which is cyclic and engages melanocortin receptors far more broadly — the two are studied together precisely to separate MC1-mediated effects from wider melanocortin signalling. PT-141 completes the set from the MC4 side, and KPV is the alpha-MSH fragment studied on inflammatory rather than pigmentation endpoints.
Purity and third-party testing
Every batch is independently analysed by Testides and Peptide Test Canada and ships with a certificate of analysis reporting high-performance liquid chromatography purity and mass-spectrometry identity. See how to read a certificate of analysis and what a purity figure actually means; our full process is on the Research and Quality page.
Handling and storage
Kept cold and protected from light while lyophilized; refrigerated and used within a shorter window once reconstituted. The storage guide covers both states, and bacteriostatic vs. sterile water explains why bacteriostatic water is the usual diluent for a vial accessed more than once.
Related research compounds
Melanotan I sits among the melanocortin references in our full catalogue, alongside GHK-Cu in skin-model research. New to this area? Start with Peptides 101, check the rules on research peptides in Canada, or browse the knowledge hub.
Research Use Only. Supplied strictly for in-vitro laboratory research and development. Not for human or animal consumption, diagnostic, or therapeutic use.
Frequently asked
No. Melanotan I is supplied strictly as a reference material for in-vitro laboratory research. It is not for human or animal consumption and is not intended for diagnostic or therapeutic use.
Yes. Every batch is independently tested by Testides and Peptide Test Canada for HPLC purity and mass-spectrometry identity, and ships with a batch-specific certificate of analysis (COA).
Melanotan I is available in 10 mg. Per-vial pricing is shown on this page.
Melanotan I is supplied as lyophilized powder. Use the reconstitution calculator to work out concentration and dosing volumes for your research, and see the storage and handling guide for temperature and shelf-life guidance. Store the lyophilized vial at -20 degrees C, desiccated and protected from light.
What researchers say
No reviews yet
Be the first to review Melanotan I. A review left from the email address on an order is labelled as a verified purchase.
Write a review
Please review the material itself — purity, packaging, shipping and handling. We cannot publish reviews describing human or animal use, dosing, or health outcomes, because everything we supply is strictly for in-vitro laboratory research. Every review is read before it appears.
