Epithalon
Tetrapeptide (Epithalon) investigated in telomerase, circadian and cellular-aging research. High-purity reference material, third-party tested with a batch COA. Research Use Only.
| Sequence / Formula | C14H22N4O9 |
|---|---|
| CAS / Reference No. | 307297-39-8 |
| Purity (HPLC) | ≥ 99.1% |
| Available sizes | 10 mg, 50 mg |
| Physical form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
What is Epithalon?
Epithalon (also spelled epitalon) is a synthetic tetrapeptide — Ala-Glu-Asp-Gly, just four residues — modelled on epithalamin, a peptide extract of the pineal gland characterised in Russian research from the 1980s onward. Its brevity makes it one of the simplest and most stable compounds in the catalogue.
It is supplied as a lyophilized powder in a sealed vial and reconstituted before in-vitro work. Our reconstitution guide covers technique and the reconstitution calculator handles the dilution for either vial size.
Research context
Epithalon is one of the most-referenced compounds in cellular-aging research, principally for its proposed effect on telomerase activity and telomere maintenance in cultured cells. A second line of work examines pineal and neuroendocrine regulation, including circadian signalling — the two strands connect through the pineal origin of the parent extract.
In longevity study designs it is most often examined alongside NAD+, which addresses cellular aging through energy metabolism rather than telomere biology, and Glutathione on the oxidative-stress side. The circadian angle puts it near DSIP.
Purity and third-party testing
Every batch is independently analysed by Testides and Peptide Test Canada and ships with a certificate of analysis reporting high-performance liquid chromatography purity and mass-spectrometry identity. See how to read a certificate of analysis and what a purity figure actually means; our full process is on the Research and Quality page.
Handling and storage
Lyophilized epithalon is kept cold and away from light; reconstituted vials are refrigerated and have a much shorter usable window. The storage guide covers both states, and bacteriostatic vs. sterile water explains why bacteriostatic water is the usual diluent for a vial accessed more than once.
Related research compounds
Epithalon anchors our longevity research collection, which also includes SS-31 and Thymalin. New to this area? Start with Peptides 101 or browse the full knowledge hub.
Research Use Only. Supplied strictly for in-vitro laboratory research and development. Not for human or animal consumption, diagnostic, or therapeutic use.
Frequently asked
No. Epithalon is supplied strictly as a reference material for in-vitro laboratory research. It is not for human or animal consumption and is not intended for diagnostic or therapeutic use.
Yes. Every batch is independently tested by Testides and Peptide Test Canada for HPLC purity and mass-spectrometry identity, and ships with a batch-specific certificate of analysis (COA).
Epithalon is available in 10 mg, 50 mg. Per-vial pricing is shown on this page.
Epithalon is supplied as lyophilized powder. Use the reconstitution calculator to work out concentration and dosing volumes for your research, and see the storage and handling guide for temperature and shelf-life guidance. Store the lyophilized vial at -20 degrees C, desiccated and protected from light.
What researchers say
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