Open full COA (PDF)Retatrutide
Investigational triple GIP / GLP-1 / glucagon receptor agonist referenced in metabolic research models.
| Sequence / Formula | C221H342N46O68 |
|---|---|
| CAS / Reference No. | 2381089-83-2 |
| Purity (HPLC) | ≥ 99.96% |
| Available sizes | 5 mg, 10 mg, 15 mg (out of stock), 20 mg |
| Physical form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
What is Retatrutide?
Retatrutide is an investigational triple-agonist research peptide that engages three receptors at once: GIP, GLP-1 and glucagon. That third target — the glucagon receptor — is what separates it from dual agonists and is the main reason it attracts attention in metabolic research.
It is supplied as a lyophilized powder and reconstituted before in-vitro use. Our reconstitution guide and calculator cover preparation.
Research context
The incretin pathways — GIP and GLP-1 — are central to research on glucose regulation and energy balance. Adding glucagon-receptor activity to that pair is of particular interest in energy-expenditure models, which is why triple agonists are studied separately from the dual-agonist class.
The closest comparison in this catalogue is Tirzepatide, a dual GIP/GLP-1 agonist. Our Retatrutide vs. Tirzepatide comparison explains the receptor differences, and the researcher overview of metabolic research peptides gives background on the class as a whole.
Purity and third-party testing
Every batch is independently analysed by Testides and Peptide Test Canada with a certificate of analysis reporting HPLC purity and mass-spectrometry identity. See how to read a certificate of analysis and peptide purity explained, or read about our process on the Research and Quality page.
Handling and storage
Store the lyophilized vial cold and protected from light. After reconstitution, shelf life is shorter and refrigeration is required — see the storage guide and bacteriostatic vs. sterile water.
Related research compounds
Retatrutide sits in our metabolic and weight research collection with Tirzepatide, Cagrilintide and MOTS-c. New to the area? Start with Peptides 101 or the knowledge hub.
Research Use Only. Supplied strictly for in-vitro laboratory research and development. Not for human or animal consumption, diagnostic, or therapeutic use.
Frequently asked
No. Retatrutide is supplied strictly as a reference material for in-vitro laboratory research. It is not for human or animal consumption and is not intended for diagnostic or therapeutic use.
Yes. Every batch is independently tested by Testides and Peptide Test Canada for HPLC purity and mass-spectrometry identity, and ships with a batch-specific certificate of analysis (COA).
Retatrutide is available in 5 mg, 10 mg, 15 mg, 20 mg. Per-vial pricing is shown on this page.
Retatrutide is supplied as lyophilized powder. Use the reconstitution calculator to work out concentration and dosing volumes for your research, and see the storage and handling guide for temperature and shelf-life guidance. Store the lyophilized vial at -20 degrees C, desiccated and protected from light.
What researchers say
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Please review the material itself — purity, packaging, shipping and handling. We cannot publish reviews describing human or animal use, dosing, or health outcomes, because everything we supply is strictly for in-vitro laboratory research. Every review is read before it appears.
